Zhejiang Shifang Pipe Industry Co.,Ltd

Zhejiang Shifang Pipe Industry Co.Ltd is one of the most professional manufacturer and exporter of roof drainage system..

Home > News > Content
Gene Editing Babies Bombarded By Trench Environment 'cross-border Gene Injection'rose And Fell Yesterday
- Nov 28, 2018 -

The National Health and Health Commission responded late yesterday, asking relevant departments to investigate and verify carefully.

Yesterday, the news of the birth of the world's first HIV-immune gene editor baby was brushed on the screen. People eating melons were shocked by the "historic breakthrough in the application of gene editing technology in disease prevention", but experts in the medical field questioned the study. More than 100 scientists issued a joint statement to "bombard" it. "

Dr. Xiao Xinye, deputy general manager of Jiyuan Gene, said in an interview with the Journal of Securities that the research was carried out without solving technical and ethical problems and was very irresponsible.

Yesterday, He Jiankui's Youku video account "He Jiankui Lab" updated five videos. In the video "Designing Babies" is a misunderstanding, He Jiankui said that history will prove that ethics is on our side.

It is reported that Shenzhen Hemei Hospital of Gynecology and Pediatrics, which accepted the medical ethics review of the research, was investigated by Shenzhen Medical Ethics Expert Committee yesterday.

Late yesterday evening, the official website of the State Health and Health Commission issued a response saying that it immediately requested the Guangdong Health and Health Commission to investigate and verify the results carefully, handle them in accordance with the law and regulations in accordance with the principles of high responsibility for people's health and science, and publicize the results to the community in a timely manner.

1. Technological and ethical problems have been "bombarded"

Yesterday, media reports said that one day before the Second International Human Genome Editorial Summit, He Jiankui, an associate professor of biology at Southern University of Science and Technology, announced that a pair of gene editing babies named Lulu and Nana were born healthily in China in November. A gene of the twins has been modified to make them naturally resistant to AIDS after birth.

A stone stirs up a thousand waves! Once the news comes out, it immediately attracts the attention of all walks of life.

"When I saw this news in the morning, I felt that it was impossible. There were two main reasons. One was that the technology was not mature enough, and the other was that ethical problems could not be solved." Dr. Xiao Xinye told the Securities Daily, "There are 3 billion pairs of bases in a very small nucleus, each of which represents a genetic code. It is very difficult to find specific fragments to edit accurately. A team at home and abroad has been doing this research, because of the'miss risk', the technical invention team has repeatedly called for the suspension of this research.

Simply put, he says, miss-target is mispositioning the target gene and editing where it should not be edited. If miss-distance occurs, the impact may be unpredictable.

"There are five levels of human utilization of genetic technology: storage, reading, understanding, use and writing. At the level of "understanding", there are ethical problems, such as whether we should tell a child under 18 years of age in advance that he may get some kind of cancer in the future, and at the level of "writing", the requirement of technology is very high, and the discussion of ethics is still very elementary. This research has gone beyond the ethical discussion and technical limitations and carried out directly, which is obviously very unreasonable. Xiao Xinye said so.

Yesterday evening, 122 scientists issued a joint statement through "intellectuals" on microblog, calling the biomedical ethics review of the so-called research a null and void. Direct human experimentation can only be described as madness. "This technology can be done long ago without any innovation, but biomedical scientists around the world do not do it and dare not do it because of the uncertainty of miss-distance, other huge risks and more important ethics. The state must quickly legislate and strictly supervise. Pandora's box has been opened. We may have a chance to close it before it can't be recovered.

He Jiankui's Southern University of Science and Technology also issued a statement saying that the research work was carried out outside the school for Professor He Jiankui, and did not report to the school and its biology department, which the school and biology department did not know about. As for Professor He Jiankui's application of gene editing technology in human embryo research, the Academic Committee of the Department of Biology believes that it seriously violates academic ethics and academic norms. Southern University of Science and Technology strictly requires scientific research to abide by national laws and regulations, respect and abide by international academic ethics and academic norms.

2. Ethical investigations have been initiated

According to the open application form of medical ethics committee, He Jiankui's research was examined and approved by the medical ethics committee of Shenzhen and Meimei Hospital of Gynecology and Pediatrics, which said that it was in accordance with ethical norms and agreed to carry out. However, whether the hospital has such qualifications has also been questioned.

Yesterday, the official Weixin of Shenzhen Health Planning Commission said that according to the principle that medical and health institutions should file with their own registration authorities within three months from the date of the establishment of the ethics committee, the medical ethics committee of Shenzhen and American Gynecological and Pediatric Hospital failed to file as required. The Shenzhen Medical Ethics Expert Committee launched an ethical investigation on the incident on November 26 to verify the authenticity of the ethical review of the research project reported by the media. The results of the investigation will be published to the public in time.

Relevant directors of Shenzhen Hemei Gynecological and Pediatric Hospital responded to the media and are investigating the matter. The genetic editing of infants is not carried out in the hospital, nor is the baby born in the hospital.

According to the enterprise survey, He Jiankui has served as the legal person of six of the nine companies. He has two companies related to gene testing under his name, namely Shenzhen Hanhai Gene Biotechnology Co., Ltd. (hereinafter referred to as "Hanhai Gene") and Shenzhen Inhe Biotechnology Co., Ltd. (hereinafter referred to as "Hanhai Gene").

In response, the trench environment response media said that in 2016 and 2017, the company invested in Fuzhou Bauhinia Strait Technology Partnership (referred to as "Fuzhou Strait"), the latter further invested in Hanhai Gene, but the company is mainly engaged in public utilities and environmental protection.

According to the semi-annual report of the trench environment, the company invested 9 million yuan in Fuzhou Strait, with a share-holding ratio of 3.75%. According to public data, Hanhai Gene is a biotechnology company, which was founded in 2012 by a team of PhD students from Stanford University and University of Michigan, and incubated by Southern University of Science and Technology. It has been invested by the fund of Zhengwei International Group, the world's top 500, and Enlightenment Venture Capital Management (Beijing) Co., Ltd.

Influenced by this news, yesterday afternoon, trench environment stock prices rose and fell sharply, closing at 4.19 yuan per share.